Orchid in pact with Merck & Co to develop novel anti-infective drugs

29 September 2008

Chennai: Orchid Chemicals & Pharmaceuticals Ltd has established a strategic research collaboration and license agreement with Merck & Co., in India through its owned affiliate, MSD Pharmaceuticals Pvt. Ltd, a marketer and distributor of Merck pharmaceutical products in India.

The agreement is for the discovery, development and commercialisation of novel agents for the treatment of bacterial and fungal infections.

Orchid Research Laboratories, the wholly-owned drug discovery subsidiary of Orchid, and Merck will work to identify and develop novel antibacterial and anti fungal compounds as clinically validated drug candidates. Orchid will undertake discovery and candidate development through Phase IIa human clinical trials, based on the results, Merck will conduct late-stage clinical development and commercialisation if regulatory approval is granted.

Under the terms of the agreement, Orchid will be paid an undisclosed upfront sum, and is eligible to receive payments totaling more than $100 million associated with the achievement of various research and development milestones.

The agreement envisages that Merck and Orchid will work on multiple targets and compounds, which will be evaluated against specific criteria for discovery and development. Orchid is also eligible to receive significant royalties on worldwide net sales of any products commercialised under the agreement.

''We have established a world class infrastructure for discovery and development of new drug candidates," said K Raghavendra Rao, managing director, Orchid Chemicals & Pharmaceuticals Ltd. ''We are extremely happy that Merck has chosen to collaborate with us to leverage our anti-infectives discovery, development and manufacturing capabilities to bring new anti-infective medicines to meet global healthcare needs.''